$11.4 million NIH grant advances drug to treat nicotine addiction

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Camino Pharma, LLC and University of California San Diego School of Medicine have been awarded an $11.4 million grant from the National Institute on Drug Abuse (NIDA) at the National Institutes of Health (NIH) to advance a novel drug candidate for nicotine addiction into first-in-human Phase 1 studies. The drug targets a neuronal signaling pathway underlying addictive behaviors, and would be a first-in-class medication to help people quit smoking.

UTEP Partnership Receives Federal Grant to Combat Opioid Abuse in West Texas Counties

Original post: Newswise - Drug and Drug Abuse UTEP Partnership Receives Federal Grant to Combat Opioid Abuse in West Texas Counties

Newswise imageThe University of Texas at El Paso’s Minority AIDS Research Center (MARC) is the subrecipient of a $1 million implementation grant to target substance use disorders and opioid use disorders in five rural counties along the Texas-Mexico border.

Abandoned Buildings, Fear of Calling Police Contribute to High Rate of Fatal Overdoses in Philadelphia, New Study Shows

Abandoned Buildings, Fear of Calling Police Contribute to High Rate of Fatal Overdoses in Philadelphia, New Study Shows

People with Heroin Addiction Have Unique Molecular Alterations to The Brain That Resemble Brain Disturbances Seen in Neurodegenerative Disorders Like Alzheimer’s Disease

Virtual Reality Trains Public to Reverse Opioid Overdoses

Original post: Newswise - Drug and Drug Abuse Virtual Reality Trains Public to Reverse Opioid Overdoses

The United States has seen a 200% increase in the rate of deaths by opioid overdose in the last 20 years. But many of these deaths were preventable. Naloxone, also called Narcan, is a prescription drug that reverses opioid overdoses, and in more than 40 states — including Pennsylvania — there is a standing order policy, which makes it available to anyone, without an individual prescription from a healthcare provider.

Potent Drug Supply Drop, Not U.S. Domestic Drug Policies, Likely Behind 2018’s Overdose Death Downturn

Original post: Newswise - Drug and Drug Abuse Potent Drug Supply Drop, Not U.S. Domestic Drug Policies, Likely Behind 2018's Overdose Death Downturn

The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the opioid epidemic, a University of Pittsburgh Graduate School of Public Health analysis revealed today.

University of Miami Miller School Researcher Wins NIH Avenir Award to Pursue Innovative Opioid Addiction Research

Luis M. Tuesta, Ph.D., assistant professor in the Department of Psychiatry and Behavioral Sciences at the University of Miami Miller School of Medicine, has been awarded the Avenir Award from the National Institute on Drug Abuse, part of the National Institutes of Health, to study the epigenetic mechanisms of microglial activation and their role in shaping the behavioral course of opioid use disorder.

Sexual Minority Men Who Smoke Report Worse Mental Health and More Frequent Substance Use

Original post: Newswise - Substance Abuse Sexual Minority Men Who Smoke Report Worse Mental Health and More Frequent Substance Use

Cigarette smoking is associated with frequent substance use and poor behavioral and physical health in sexual and gender minority populations, according to Rutgers researchers.