Experts to Discuss the Essential Efforts of Clinical Laboratories to Fight the Opioid Epidemic at the 2020 AACC Annual Scientific Meeting

The opioid epidemic has only gotten worse since the advent of COVID-19, with some areas in the U.S. reporting a 50% increase in drug overdoses due to the pandemic. With no end in sight to this public health crisis, scientific sessions during the virtual 2020 AACC Annual Scientific Meeting & Clinical Lab Expo will highlight the integral role of clinical laboratories in efforts to manage it, as well as the latest drug tests needed to do so.

Novel Anti-Craving Mechanism Discovered to Treat Cocaine Relapse

Original post: Newswise - Drug and Drug Abuse Novel Anti-Craving Mechanism Discovered to Treat Cocaine Relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder. Specifically, GLP-1R agonists, which are FDA-approved for treating diabetes and obesity, have been shown to reduce voluntary drug taking and seeking in preclinical models of cocaine used disorder. However, the exact neural circuits and cell types that mediate the suppressive effects of GLP-1R agonists on cocaine-seeking behavior are mostly unknown.

After CDC guidance, little change in opioid prescriptions to those at risk of misuse

Original post: Newswise - Drug and Drug Abuse After CDC guidance, little change in opioid prescriptions to those at risk of misuse

Newswise imageResearch from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a schedule II opioid for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC).

Circadian Gene Mutation Increases Self-Administration of Cocaine in Mice

Original post: Newswise - Substance Abuse Circadian Gene Mutation Increases Self-Administration of Cocaine in Mice

University of Pittsburgh researchers reveal a molecular basis for the deep and fundamental connection between the disruption in circadian rhythms and predisposition to substance abuse.

Bridging the Gap: Phone-Based Continuing Care Reduces Relapse Following Residential Treatment for Alcohol Use Disorder

High-frequency telephone support from a familiar psychotherapist reduces the risk of relapse after inpatient treatment for alcohol use disorder (AUD), according to a study reported in Alcoholism: Clinical and Experimental Research. Many patients resume drinking within the first few months after residential treatment, so continuous care in this high-risk period is crucial. Typically, this involves face-to-face counselling, but compliance is often low and there is a need for alternative options to improve outcomes during the vulnerable phase. Individualized phone-based support from staff or volunteers, and automated text message-based support, are two lower-cost and user-friendly approaches. In pilot studies these appear to be well accepted and feasible, but data on efficacy have varied, probably because of differences in program delivery and patient populations. The latest study compared the effectiveness of phone and text-based continuing care programs following a 12-week residential A

People who Use Alcohol and Cannabis Together May Reduce Risks by Choosing Certain Products and Combinations

Young adults who combine alcohol and cannabis use experience fewer negative consequences when they stick with a single type of drink versus consuming multiple types of alcohol, according to a new study. In addition, by avoiding cannabis concentrate they may steady or lower their overall consumption. The findings suggest that for those who choose to sustain their levels of alcohol and cannabis use, judicious choice of products may reduce the risks.