Restricting Ketamine Would Have ‘Dire Consequences’ for Surgery in Low-Resource Countries, Anesthesiologists Warn

Proposals to restrict access to ketamine by making it a “Schedule I” drug would have a major impact on the availability of anesthesia and surgery in low- to middle-income countries (LMICs)–where ketamine is often the only general anesthetic drug available, according to a series of commentaries in Anesthesia & Analgesia.

The Dose Makes the Poison: Opioid Overdose Study Supports Call for Caution in Prescription Levels

Original post: Newswise - Drug and Drug Abuse The Dose Makes the Poison: Opioid Overdose Study Supports Call for Caution in Prescription Levels

When it comes to prescription painkillers, the difference between controlling pain and dying from an overdose may come down to how strong a prescription the doctor wrote, according to a new study in veterans. And the threshold for safe prescribing may be lower than most people think – or than most guidelines recommend.

Violent Crime Lower Near Drug Treatment Centers Than Other Commercial Areas

Original post: Newswise - Drug and Drug Abuse Violent Crime Lower Near Drug Treatment Centers Than Other Commercial Areas

New Johns Hopkins Bloomberg School of Public Health research suggests there may actually be less serious crime near outpatient drug treatment clinics than other community businesses.

Legal, Policy Changes Can Lead to Shifts in Use of Medical Marijuana

Original post: Newswise - Drug and Drug Abuse Legal, Policy Changes Can Lead to Shifts in Use of Medical Marijuana

A Johns Hopkins Bloomberg School of Public Health analysis of registered medical marijuana users found that a hodgepodge of law and policy changes since 2001 had varying effects on the number of people consuming what in many states remains an otherwise illegal drug for its purported health benefits.

New Evidence in Mice That Cocaine Makes Brain Cells Cannibalize Themselves

Original post: Newswise - Drug and Drug Abuse New Evidence in Mice That Cocaine Makes Brain Cells Cannibalize Themselves

Working with mice, researchers have contributed significant new evidence to support the idea that high doses of cocaine kill brain cells by triggering overactive autophagy, a process in which cells literally digest their own insides. Their results, moreover, bring with them a possible antidote.

Cocaine Addiction: Scientists Discover ‘Back Door’ Into the Brain

Original post: Newswise - Drug and Drug Abuse Cocaine Addiction: Scientists Discover 'Back Door' Into the Brain

Individuals addicted to cocaine may have difficulty in controlling their addiction because of a previously-unknown ‘back door’ into the brain, circumventing their self-control, suggests a new study led by the University of Cambridge.

Two-in-One Packaging May Increase Drug Efficacy and Reduce Side Effects

Original post: Newswise - Drug and Drug Abuse Two-in-One Packaging May Increase Drug Efficacy and Reduce Side Effects

Researchers have developed a speedy, controllable way to get two or more ingredients into the same tiny capsule and only have them mix when triggered by a signal like vibrations or heat