Not Even a Puff: More Smokers Kick the Habit With Extended Nicotine Patch Therapy

New research from the University of Pennsylvania School of Medicine may help more smokers keep their New Year’s resolution by helping them quit smoking. Extended use of a nicotine patch – 24 weeks versus the standard eight weeks recommended by manufacturers – boosts the number of smokers who maintain their cigarette abstinence and helps more of those who backslide into the habit while wearing the patch, according to a study which will be published in the February 2 issue of Annals of Internal Medicine.

Cocaine Exposure During Pregnancy Leads to Impulsivity in Male, Not Female, Monkeys

Adult male monkeys exposed to cocaine while in the womb have poor impulse control and may be more vulnerable to drug abuse than female monkeys, even a decade or more after the exposure, according to a new study by researchers at Wake Forest University School of Medicine. The findings could lead to a better understanding of human drug abuse.

Research Probes Genetic Underpinnings of Nicotine Addiction

A new study from the Abramson Cancer Center and Department of Psychiatry in the University of Pennsylvania School of Medicine shows that smokers who carry a particular version of a gene for an enzyme that regulates dopamine in the brain may suffer from concentration problems and other cognitive deficits when abstaining from nicotine “” a problem that puts them at risk for relapse during attempts to quit smoking. The findings pave the way to identify novel medications to treat nicotine addiction.

Study Examines Sensation Seeking Behavior, Addiction and Smoking Cessation

The tendency to become addicted to nicotine and other drugs involves an interplay of genetics and environmental factors. In a unique study looking at the chemistry underlying the propensity to develop nicotine craving, scientists are gaining insight into predicting individual addiction to nicotine, forecasting nicotine tumorigenesis, and developing individualized treatments for this disorder.

Mixing Large Doses of Both Acetaminophen Painkiller and Caffeine May Increase Risk of Liver Damage

Consuming large amounts of caffeine while taking acetaminophen, a widely used painkiller, could potentially cause liver damage, according to a preliminary laboratory study. The toxic interaction could occur not only from drinking caffeinated beverages while taking the painkiller but also from using large amounts of medications that intentionally combine caffeine and acetaminophen, the researchers say.